Primary Hypercholesteremia Compared to Combined Hypercholesteremia and Hypertriglyceridemia

Difference in bile acid excretion. Primary hypercholesteremia compared to combined hypercholesteremia and hypertriglyceridemia.

Total daily bile acid excretion was measured in 10 patients with primary hypercholesteremia and in nine patients with combined hypercholesteremia and hypertriglyceridermia by using "GC-labeled cholic acid and 3H-labeled chenodeoxycholic acid. The average bile acid excretion by the patients with primary hypercholesteremia was 282 mg/day; that by the patients with combined hypercholesteremia and ...

Observations concerning the Cholate: Cholesterol Relationship

The occurrence of hypercholesteremia in the nephrotic state is a long recognized phenomenon (1), but its mechanism remains to be determined. Apparently the hypercholesteremia cannot be ascribed to a primary "lipoid degeneration" of the kidney (2). Recently, studies from this laboratory (3-6) have indicated that there is a marked derangement of cholate metabolism in certain clinical and experime...

A Comparison of lhe Hypercholesleremia Produced by Biliary Obstruction with That Produced by Continuous Intravenous Injection of Cholate

Previous studies from this laboratory (1, 2) have indicated that when the cholate content of the rat 's plasma is elevated, either by biliary obstruction or by the continuous intravenous injection of cholate into normal rats, a hypercholesteremia promptly appears. Moreover, excess cholate was found in the plasma of patients suffering from various states involving hypercholesteremia (3). These f...

Coagulation and Fibrinolysis in Patients with Idiopathic Hyperlipemia and Primary Hypercholesteremia before and after a Fatty Meal

In view of the current interest in the possible relationship between elevated serum lipid levels, increased coagulability of the blood (or decreased blood fibrinolysis) and ischemic heart disease, the clotting and fibrinolytic activity of the blood were studied before and after a fatty meal in 9 patients with idiopathic hyperlipemia, 10 patients with primary hypercholesteremia, and 10 normal su...

Studies of blood coagulation and fibrinolysis in patients with idiopathic hyperlipemia and primary hypercholesteremia before and after a fatty meal.